Introduction

normalized NLR count

Growth

Growth curve

Area under the curve

## `summarise()` has grouped output by 'KO'. You can override using the `.groups`
## argument.
KO Filter_ID AUC
Blue 20230501/MKN45/PBMCs D1/CEA-TCB/- 7287552
Blue 20230501/MKN45/PBMCs D2/CEA-TCB/- 8774893
Blue 20230501/MKN45/PBMCs D3/CEA-TCB/- 6916298
Blue 20230501/MKN45/PBMCs D4/CEA-TCB/- 9284429
Green 20230501/MKN45/PBMCs D1/CEA-TCB/- 8466275
Green 20230501/MKN45/PBMCs D2/CEA-TCB/- 7940839
Green 20230501/MKN45/PBMCs D3/CEA-TCB/- 3866721
Green 20230501/MKN45/PBMCs D4/CEA-TCB/- 4584777
Orange 20230501/MKN45/PBMCs D1/CEA-TCB/- 11475883
Orange 20230501/MKN45/PBMCs D2/CEA-TCB/- 12490358
Orange 20230501/MKN45/PBMCs D3/CEA-TCB/- 9920774
Orange 20230501/MKN45/PBMCs D4/CEA-TCB/- 8832324
Pos. ctrl 20230501/MKN45/PBMCs D1/CEA-TCB/- 17768375
Pos. ctrl 20230501/MKN45/PBMCs D2/CEA-TCB/- 16501387
Pos. ctrl 20230501/MKN45/PBMCs D3/CEA-TCB/- 13852846
Pos. ctrl 20230501/MKN45/PBMCs D4/CEA-TCB/- 14042435
Purple 20230501/MKN45/PBMCs D1/CEA-TCB/- 8078002
Purple 20230501/MKN45/PBMCs D2/CEA-TCB/- 6749528
Purple 20230501/MKN45/PBMCs D3/CEA-TCB/- 3672978
Purple 20230501/MKN45/PBMCs D4/CEA-TCB/- 3306923
Scr_high 20230501/MKN45/PBMCs D1/CEA-TCB/- 18796406
Scr_high 20230501/MKN45/PBMCs D2/CEA-TCB/- 16139231
Scr_high 20230501/MKN45/PBMCs D3/CEA-TCB/- 15263737
Scr_high 20230501/MKN45/PBMCs D4/CEA-TCB/- 15461650
Scr_higher 20230501/MKN45/PBMCs D1/CEA-TCB/- 12283676
Scr_higher 20230501/MKN45/PBMCs D2/CEA-TCB/- 6165890
Scr_higher 20230501/MKN45/PBMCs D3/CEA-TCB/- 9565769
Scr_higher 20230501/MKN45/PBMCs D4/CEA-TCB/- 6764481
Scr_low 20230501/MKN45/PBMCs D1/CEA-TCB/- 16522798
Scr_low 20230501/MKN45/PBMCs D2/CEA-TCB/- 15678339
Scr_low 20230501/MKN45/PBMCs D3/CEA-TCB/- 12432741
Scr_low 20230501/MKN45/PBMCs D4/CEA-TCB/- 11630173
Scr_mid 20230501/MKN45/PBMCs D1/CEA-TCB/- 9797703
Scr_mid 20230501/MKN45/PBMCs D2/CEA-TCB/- 10124519
Scr_mid 20230501/MKN45/PBMCs D3/CEA-TCB/- 3829163
Scr_mid 20230501/MKN45/PBMCs D4/CEA-TCB/- 5022985
Yellow 20230501/MKN45/PBMCs D1/CEA-TCB/- 5575144
Yellow 20230501/MKN45/PBMCs D2/CEA-TCB/- 6472994
Yellow 20230501/MKN45/PBMCs D3/CEA-TCB/- 4786186
Yellow 20230501/MKN45/PBMCs D4/CEA-TCB/- 8071852

killing plots

The following analysis is plotting each sample with its corresponding control based on similar growth and seeding. The area under the curve (AUC) was calculated for each cell line and each seeding control. The difference in AUC (AUC delta) between sample and each seeding control was then calculated. The smallest AUC delta corresponds to the most similar growth and seeding. Therefore the samples where assigned to the controls based on their smallest AUC delta and graphs were plotted accordingly.

Samples only with Scr low

Blue

PBMCs D4

CEA-TCB

PBMCs D1

CEA-TCB

PBMCs D2

CEA-TCB

PBMCs D3

CEA-TCB

Samples only with Scr mid

Green

PBMCs D1

CEA-TCB

PBMCs D3

CEA-TCB

PBMCs D4

CEA-TCB

PBMCs D2

CEA-TCB

Purple

PBMCs D1

CEA-TCB

PBMCs D3

CEA-TCB

PBMCs D4

CEA-TCB

PBMCs D2

CEA-TCB

Orange

PBMCs D2

CEA-TCB

PBMCs D1

CEA-TCB

PBMCs D3

CEA-TCB

PBMCs D4

CEA-TCB

Yellow

PBMCs D1

CEA-TCB

PBMCs D3

CEA-TCB

PBMCs D2

CEA-TCB

PBMCs D4

CEA-TCB

Blue

PBMCs D1

CEA-TCB

PBMCs D2

CEA-TCB

PBMCs D3

CEA-TCB

PBMCs D4

CEA-TCB

Samples only with Scr high

Pos. ctrl

PBMCs D1

CEA-TCB

PBMCs D2

CEA-TCB

PBMCs D3

CEA-TCB

PBMCs D4

CEA-TCB

Samples only with Scr higher

Orange

PBMCs D1

CEA-TCB

PBMCs D3

CEA-TCB

PBMCs D4

CEA-TCB

PBMCs D2

CEA-TCB

Green

PBMCs D2

CEA-TCB

PBMCs D1

CEA-TCB

PBMCs D3

CEA-TCB

PBMCs D4

CEA-TCB

Purple

PBMCs D2

CEA-TCB

PBMCs D1

CEA-TCB

PBMCs D3

CEA-TCB

PBMCs D4

CEA-TCB

Yellow

PBMCs D2

CEA-TCB

PBMCs D4

CEA-TCB

PBMCs D1

CEA-TCB

PBMCs D3

CEA-TCB

Blue

PBMCs D3

CEA-TCB

PBMCs D1

CEA-TCB

PBMCs D2

CEA-TCB

PBMCs D4

CEA-TCB

Killing plots including all Growth controls

Pos. ctrl

PBMCs D1

CEA-TCB

PBMCs D2

CEA-TCB

PBMCs D3

CEA-TCB

PBMCs D4

CEA-TCB

Orange

PBMCs D1

CEA-TCB

PBMCs D2

CEA-TCB

PBMCs D3

CEA-TCB

PBMCs D4

CEA-TCB

Green

PBMCs D1

CEA-TCB

PBMCs D2

CEA-TCB

PBMCs D3

CEA-TCB

PBMCs D4

CEA-TCB

Purple

PBMCs D1

CEA-TCB

PBMCs D2

CEA-TCB

PBMCs D3

CEA-TCB

PBMCs D4

CEA-TCB

Yellow

PBMCs D1

CEA-TCB

PBMCs D2

CEA-TCB

PBMCs D3

CEA-TCB

PBMCs D4

CEA-TCB

Blue

PBMCs D1

CEA-TCB

PBMCs D2

CEA-TCB

PBMCs D3

CEA-TCB

PBMCs D4

CEA-TCB

Facet Grid per Gene by Donor

Blue

Green

Purple

Orange

Yellow

Blue

Pos. ctrl

Orange

Green

Purple

Yellow

Blue

[[1]] NULL

[[2]] NULL

[[3]] NULL

[[4]] NULL